Glucagon-like peptide-1, or GLP-1, receptor agonists have transformed the way medicine approaches weight management and metabolic health. Medications such as Semaglutide, Tirzepatide, and Liraglutide are now widely prescribed for obesity, insulin resistance, and type 2 diabetes, offering patients effective tools to achieve significant weight reduction. As these therapies have become more popular, aesthetic providers have begun observing predictable changes in the skin that often accompany rapid or substantial weight loss. While GLP-1 medications do not directly age the skin, the physiological consequences of fat reduction, caloric restriction, and metabolic shifts can influence facial contours, overall skin laxity, and hair quality, making a nuanced understanding of these effects increasingly important for those in aesthetic practice.
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